Ontology highlight
ABSTRACT:
SUBMITTER: Mumaw J
PROVIDER: S-EPMC3296315 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Mumaw Jennifer J Jordan Erin T ET Sonnet Corinne C Olabisi Ronke M RM Olmsted-Davis Elizabeth A EA Davis Alan R AR Peroni John F JF West Jennifer L JL West Franklin F Lu Yangqing Y Stice Steven L SL
International journal of biomaterials 20120207
Autologous bone grafting is the most effective treatment for long-bone nonunions, but it poses considerable risks to donors, necessitating the development of alternative therapeutics. Poly(ethylene glycol) (PEG) microencapsulation and BMP2 transgene delivery are being developed together to induce rapid bone formation. However, methods to make these treatments available for clinical applications are presently lacking. In this study we used mesenchymal stem cells (MSCs) due to their ease of harves ...[more]