Ontology highlight
ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC3299414 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Lu Jin J Wang Wei W Wang Shaopeng S Shan Xiaonan X Li Jinghong J Tao Nongjian N
Analytical chemistry 20111214 1
Plasmonic-based electrochemical impedance spectroscopy (P-EIS) is developed to investigate molecular binding on surfaces. Its basic principle relies on the sensitive dependence of surface plasmon resonance (SPR) signal on surface charge density, which is modulated by applying an ac potential to a SPR chip surface. The ac component of the SPR response gives the electrochemical impedance, and the dc component provides the conventional SPR detection. The plasmonic-based impedance measured over a ra ...[more]