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Emergence and dissemination of a swine H3N2 reassortant influenza virus with 2009 pandemic H1N1 genes in pigs in China.


ABSTRACT: The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong, China. Genetic and epidemiological analyses suggest that these viruses have circulated in swine for some time. This is the first evidence that swine reassortant viruses with pdm/09-like genes may have become established in the field, altering the landscape of human and swine influenza.

SUBMITTER: Fan X 

PROVIDER: S-EPMC3302387 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Emergence and dissemination of a swine H3N2 reassortant influenza virus with 2009 pandemic H1N1 genes in pigs in China.

Fan Xiaohui X   Zhu Huachen H   Zhou Boping B   Smith David K DK   Chen Xinchun X   Lam Tommy T-Y TT   Poon Leo L M LL   Peiris Malik M   Guan Yi Y  

Journal of virology 20111214 4


The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong, China. Genetic and epidemiological analyses suggest that these viruses have circulated in swine for some time. This is the first evidence that swine reassortant viruses with pdm/09-like genes may have become established in the field, altering the landscape of human and swi  ...[more]

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