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Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.

ABSTRACT: A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics.

SUBMITTER: Canini L

PROVIDER: S-EPMC6820103 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.

Canini Laetitia L Everett Helen E HE Aramouni Mario M Coward Vivien V Ramsay Andrew A Kelly Michael M Morgan Sophie S Tchilian Elma E Gilbert Sarah S Charleston Bryan B Brown Ian H IH Brookes Sharon M SM Woolhouse Mark E J MEJ

Data in brief 20190928

A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics. ...[more]

PMID: 31687431

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