Ontology highlight
ABSTRACT:
SUBMITTER: International Stroke Genetics Consortium (ISGC)
PROVIDER: S-EPMC3303115 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Nature genetics 20120205 3
Genetic factors have been implicated in stroke risk, but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke and its subtypes in 3,548 affected individuals and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 affected individuals and 6,281 controls. We replicated previous associations for cardioembolic stroke near PITX2 and ZFHX3 and for large vessel stroke at a 9p21 locus. We ide ...[more]