Ontology highlight
ABSTRACT:
SUBMITTER: Chen SJ
PROVIDER: S-EPMC3306390 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Chen Shun-Jia SJ Wu Yi-Hua YH Huang Hsiao-Yun HY Wang Chien-Chia CC
PloS one 20120316 3
Aminoacyl-tRNA synthetases are a large family of housekeeping enzymes that are pivotal in protein translation and other vital cellular processes. Saccharomyces cerevisiae possesses two distinct nuclear glycyl-tRNA synthetase (GlyRS) genes, GRS1 and GRS2. GRS1 encodes both cytoplasmic and mitochondrial activities, while GRS2 is essentially silent and dispensable under normal conditions. We herein present evidence that expression of GRS2 was drastically induced upon heat shock, ethanol or hydrogen ...[more]