Ontology highlight
ABSTRACT:
SUBMITTER: Yu L
PROVIDER: S-EPMC3306495 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Yu Lei L Shulman Joshua M JM Chibnik Lori L Leurgans Sue S Schneider Julie A JA De Jager Philip L PL Bennett David A DA
Aging cell 20111229 2
The cholesteryl ester transfer protein (CETP) gene plays an essential role in regulating cholesterol homeostasis and is a candidate susceptibility gene for late-onset Alzheimer's disease (AD). Recent finding suggests that the CETP I405V polymorphism (rs5882) is associated with a slower rate of memory decline and a lower risk of incident dementia. Using data from two ongoing epidemiologic clinical-pathologic cohort studies of aging and dementia in the United States, the Religious Order Study and ...[more]