Ontology highlight
ABSTRACT:
SUBMITTER: Guyton JR
PROVIDER: S-EPMC3308290 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Guyton John R JR Fazio Sergio S Adewale Adeniyi J AJ Jensen Erin E Tomassini Joanne E JE Shah Arvind A Tershakovec Andrew M AM
Diabetes care 20120214 4
<h4>Objective</h4>To determine the effect of niacin on fasting glucose (FG) and new-onset diabetes in statin/ezetimibe-treated patients.<h4>Research design and methods</h4>This was a prespecified secondary analysis among 942 hyperlipidemic patients randomized to ezetimibe/simvastatin (E/S; 10/20 mg) or E/S + extended-release niacin (N; titrated to 2 g) over 64 weeks.<h4>Results</h4>FG levels peaked by 8-12 weeks, then declined even without antidiabetic medication. At 64 weeks, 3.5% taking E/S+N ...[more]