Ontology highlight
ABSTRACT:
SUBMITTER: Xiong W
PROVIDER: S-EPMC3314402 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Developmental dynamics : an official publication of the American Association of Anatomists 20110701 7
Coordinated differentiation and morphogenesis transform the Drosophila retina from a layer of epithelial cells into a complex three-dimensional organ. In this study we show that the Abelson (Abl) tyrosine kinase localizes to the dynamically remodeling apical-junctional membrane domains of the developing photoreceptor cells. Analyses of abl mutant clone phenotypes demonstrate that abl is required for enriched localization of adherens junction and apical polarity complex proteins at photoreceptor- ...[more]