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Immunoglobulin A nephropathy associated with Plasmodium falciparum malaria.


ABSTRACT: Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.

SUBMITTER: Yoo DE 

PROVIDER: S-EPMC3314860 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Immunoglobulin A nephropathy associated with Plasmodium falciparum malaria.

Yoo Dong Eun DE   Kim Jeong Ho JH   Kie Jeong Hae JH   Park Yoonseon Y   Chang Tae Ik TI   Oh Hyung Jung HJ   Kim Seung Jun SJ   Yoo Tae-Hyun TH   Choi Kyu Hun KH   Kang Shin-Wook SW   Han Seung Hyeok SH  

Journal of Korean medical science 20120321 4


Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laborat  ...[more]

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