Ontology highlight
ABSTRACT:
SUBMITTER: Barnes A
PROVIDER: S-EPMC3316513 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Barnes Anna A Isohanni Matti M Barnett Jennifer H JH Pietiläinen Olli O Veijola Juha J Miettunen Jouko J Paunio Tiina T Tanskanen Päivikki P Ridler Khanum K Suckling John J Bullmore Edward T ET Murray Graham K GK Jones Peter B PB
PloS one 20120330 3
We examined the effect of the catechol-O-methyltransferase (COMT) Val158Met polymorphism (rs4680), on brain structure in a subset (N = 82) of general population members of the Northern Finland 1966 Birth Cohort, selected through a randomization procedure, aged 33-35. Optimised voxel-based morphometry was used to produce grey matter maps from each subject's high resolution T1 weighted brain magnetic resonance images, which were subsequently entered into a general linear model with COMT genotype a ...[more]