Ontology highlight
ABSTRACT:
SUBMITTER: Song S
PROVIDER: S-EPMC3317984 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Journal of dental research 20090201 2
Recent studies have detected mutations in the EDA gene, previously identified as causing X-linked hypohidrotic ectodermal dysplasia (XLHED), in two families with X-linked non-syndromic hypodontia. Notably, all affected males in both families exhibited isolated oligodontia, while almost all female carriers showed a milder or normal phenotype. We hypothesized that the EDA gene could be responsible for sporadic non-syndromic oligodontia in affected males. In this study, we examined 15 unrelated mal ...[more]