Ontology highlight
ABSTRACT:
SUBMITTER: Itzhaki Z
PROVIDER: S-EPMC3317993 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Itzhaki Zohar Z Margalit Hanah H
PloS one 20120403 4
Genome sequencing of various individuals or isolates of the same species allows studying the polymorphism level of specific proteins and protein domains. Here we ask whether domains that are known to be involved in mediating protein-protein interactions show lower polymorphism than other domains. To this end we take advantage of a recent genome sequence dataset of 39 Saccahromyces cerevisiae strains and the experimentally determined protein interaction network of the laboratory strain. We analyz ...[more]