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Klebsiella pneumoniae ST258 producing KPC-3 identified in italy carries novel plasmids and OmpK36/OmpK35 porin variants.

ABSTRACT: A carbapenemase-resistant Klebsiella pneumoniae strain, clone ST258 producing KPC-3, was fully characterized. The entire plasmid content was investigated, thereby identifying plasmids of the IncFII(k) (two of them similar to pKPQIL and pKPN3, respectively), IncX, and ColE types, carrying a formidable set of resistance genes against toxic compounds, metals, and antimicrobial drugs and a novel iron(III) uptake system.

SUBMITTER: Garcia-Fernandez A

PROVIDER: S-EPMC3318348 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Klebsiella pneumoniae ST258 producing KPC-3 identified in italy carries novel plasmids and OmpK36/OmpK35 porin variants.

García-Fernández Aurora A Villa Laura L Carta Claudio C Venditti Carolina C Giordano Alessandra A Venditti Mario M Mancini Carlo C Carattoli Alessandra A

Antimicrobial agents and chemotherapy 20120117 4

A carbapenemase-resistant Klebsiella pneumoniae strain, clone ST258 producing KPC-3, was fully characterized. The entire plasmid content was investigated, thereby identifying plasmids of the IncFII(k) (two of them similar to pKPQIL and pKPN3, respectively), IncX, and ColE types, carrying a formidable set of resistance genes against toxic compounds, metals, and antimicrobial drugs and a novel iron(III) uptake system. ...[more]

PMID: 22252815

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