Ontology highlight
ABSTRACT:
SUBMITTER: Lillehoj EP
PROVIDER: S-EPMC3318723 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Lillehoj Erik P EP Hyun Sang Won SW Feng Chiguang C Zhang Lei L Liu Anguo A Guang Wei W Nguyen Chinh C Luzina Irina G IG Atamas Sergei P SP Passaniti Antonino A Twaddell William S WS Puché Adam C AC Wang Lai-Xi LX Cross Alan S AS Goldblum Simeon E SE
The Journal of biological chemistry 20120113 11
Epithelial cells (ECs) lining the airways provide a protective barrier between the external environment and the internal host milieu. These same airway epithelia express receptors that respond to danger signals and initiate repair programs. Because the sialylation state of a receptor can influence its function and is dictated in part by sialidase activity, we asked whether airway epithelia express catalytically active sialidase(s). Human primary small airway and A549 ECs expressed NEU1 sialidase ...[more]