Ontology highlight
ABSTRACT:
SUBMITTER: Sato M
PROVIDER: S-EPMC3319607 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Sato Mitsuru M Kojima Katsura K Sakuma Chisato C Murakami Maria M Aratani Eriko E Takenouchi Takato T Tamada Yasushi Y Kitani Hiroshi H
PloS one 20120404 4
Bombyx mori (silkworm) silk proteins are being utilized as unique biomaterials for medical applications. Chemical modification or post-conjugation of bioactive ligands expand the applicability of silk proteins; however, the processes are elaborate and costly. In this study, we used transgenic silkworm technology to develop single-chain variable fragment (scFv)-conjugated silk fibroin. The cocoons of the transgenic silkworm contain fibroin L-chain linked with scFv as a fusion protein. After disso ...[more]