Ontology highlight
ABSTRACT:
SUBMITTER: Lin C
PROVIDER: S-EPMC3319872 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Lin Chenxiang C Wang Xing X Liu Yan Y Seeman Nadrian C NC Yan Hao H
Journal of the American Chemical Society 20071027 46
Nature has evolved replicable biological molecules, such as DNA, as genetic information carriers. The replication process is tightly controlled by complicated cellular machinery. It is interesting to ask if artificial DNA nano-objects with a complex secondary structure can be replicated in the same way as simple DNA double helices. Here we demonstrate that paranemic crossover DNA, a structurally complicated multi-crossover DNA molecule, can be replicated successfully using Rolling Circle Amplifi ...[more]