Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy.
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ABSTRACT:
SUBMITTER: Ayoub JP
PROVIDER: S-EPMC3320230 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy.
Ayoub J P M JP Verma Sh Sh Verma Su S
Current oncology (Toronto, Ont.) 20120401 2
This article provides an overview of recent advances in chemotherapy that may be used for the treatment of patients with locally advanced or metastatic breast cancer (MBC). Key phase ii and iii trial data for eribulin mesylate, ixabepilone, and nab-paclitaxel, published since 2006, are discussed on the basis of recency, depth, and quality.Eribulin mesylate is the first monotherapy to significantly increase overall survival in patients with pretreated MBC, but nab-paclitaxel offers a novel and sa ...[more]
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