Ontology highlight
ABSTRACT:
SUBMITTER: Longworth MS
PROVIDER: S-EPMC3320600 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Longworth Michelle S MS Walker James A JA Anderssen Endre E Moon Nam-Sung NS Gladden Andrew A Heck Margarete M S MM Ramaswamy Sridhar S Dyson Nicholas J NJ
PLoS genetics 20120405 4
Previously, we discovered a conserved interaction between RB proteins and the Condensin II protein CAP-D3 that is important for ensuring uniform chromatin condensation during mitotic prophase. The Drosophila melanogaster homologs RBF1 and dCAP-D3 co-localize on non-dividing polytene chromatin, suggesting the existence of a shared, non-mitotic role for these two proteins. Here, we show that the absence of RBF1 and dCAP-D3 alters the expression of many of the same genes in larvae and adult flies. ...[more]