Ontology highlight
ABSTRACT:
SUBMITTER: Lapek JD
PROVIDER: S-EPMC3322323 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Lapek John D JD McGrath James L JL Ricke William A WA Friedman Alan E AE
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120303
This work describes the proteomic characterization of a novel in vitro prostate cancer model system, the clonal prostatic human epithelial cancer (PHEC) cell lines. The model is composed of three cell lines representing the three progressive cancer states found in vivo: non-tumorigenic, tumorigenic, and metastatic. The cell lines were evaluated for differential protein expression between states using two dimensional liquid:liquid chromatographic separation followed by mass spectral identificatio ...[more]