Trends in birth weight and gestational age for infants born to HIV-infected, antiretroviral treatment-naive women in Malawi.

ABSTRACT:

Background

We analyzed birth outcomes among infants of treatment-naive, HIV-infected women from a series of mother-to-child transmission of HIV studies in Blantyre, Malawi.

Methods

Data from 6 prospective studies at 1 research site were analyzed. Mean birth weight (BW) and gestational age (GA), and frequency of low birth weight (LBW; <2500 g) and preterm (PT) birth (GA < 37 weeks) were estimated. We assessed risk factors for LBW and PT birth using mixed-effects logistic regression. Adjusted odds ratios (AOR) and 95% confidence intervals from earlier studies (1989-1994) and later studies (2000-2007) are presented separately.

Results

The analysis included 8874 HIV-exposed infants. Mean BW and GA ranged from 2793 to 3079 g, and from 37.8 to 39.0 weeks. Greater maternal a

SUBMITTER: Taha TE 

PROVIDER: S-EPMC3329585 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature