Ontology highlight
ABSTRACT:
SUBMITTER: Huang WC
PROVIDER: S-EPMC3329964 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Neuron 20120401 1
Central neurons respond to synaptic inputs from other neurons by generating synaptic potentials. Once the summated synaptic potentials reach threshold for action potential firing, the signal propagates leading to transmitter release at the synapse. The calcium influx accompanying such signaling opens calcium-activated ion channels for feedback regulation. Here, we report a mechanism for modulating hippocampal neuronal signaling that involves calcium-activated chloride channels (CaCCs). We presen ...[more]