Ontology highlight
ABSTRACT:
SUBMITTER: Li Q
PROVIDER: S-EPMC3330829 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Li Qiang Q Ritter Deborah D Yang Nan N Dong Zhiqiang Z Li Hao H Chuang Jeffrey H JH Guo Su S
Developmental biology 20091020 2
Uncovering the cis-regulatory logic of developmental enhancers is critical to understanding the role of non-coding DNA in development. However, it is cumbersome to identify functional motifs within enhancers, and thus few vertebrate enhancers have their core functional motifs revealed. Here we report a combined experimental and computational approach for discovering regulatory motifs in developmental enhancers. Making use of the zebrafish gene expression database, we computationally identified c ...[more]