Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh AK
PROVIDER: S-EPMC3331910 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Ghosh Arun K AK Martyr Cuthbert D CD Xu Chun-Xiao CX
Organic letters 20120404 8
A new and convenient synthesis of benzo-fused 8-oxabicyclo[3.2.1]octane and 9-oxabicyclo[4.2.1]nonane derivatives are described. The reaction involved a TiCl(4)-mediated tandem carbonyl or imine addition followed by a Friedel-Crafts cyclization to provide these functionalized derivatives in good to excellent yields and high diastereoselectivity. ...[more]