Ontology highlight
ABSTRACT:
SUBMITTER: DiRocco DA
PROVIDER: S-EPMC3336740 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20120328 14
Since Breslow's initial report on the thiamine mode of action, the study of catalytic acyl carbanion processes has been an area of immense interest. With the advent of azolylidene catalysis, a plethora of reactivtiy has been harnessed, but the crucial nucleophilic intermediate proposed by Breslow had never been isolated or fully characterized. Herein, we report the isolation and full characterization of nitrogen analogues of the Breslow intermediate. Both stable and catalytically relevant, these ...[more]