Ontology highlight
ABSTRACT:
SUBMITTER: Belisle JM
PROVIDER: S-EPMC3338543 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Bélisle Jonathan M JM Levin Leonard A LA Costantino Santiago S
PloS one 20120426 4
The study of neurite guidance in vitro relies on the ability to reproduce the distribution of attractive and repulsive guidance molecules normally expressed in vivo. The identification of subtle variations in the neurite response to changes in the spatial distribution of extracellular molecules can be achieved by monitoring the behavior of cells on protein gradients. To do this, automated high-content screening assays are needed to quantify the morphological changes resulting from growth on grad ...[more]