Ontology highlight
ABSTRACT:
SUBMITTER: Mealey RH
PROVIDER: S-EPMC3342690 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Mealey Robert H RH Zhang Baoshan B Leib Steven R SR Littke Matt H MH McGuire Travis C TC
Virology 20030901 2
Equine infectious anemia virus (EIAV) is a lentivirus that causes persistent infections in horses. We hypothesized that high-avidity CTL specific for nonvariable epitopes might be associated with low viral load and minimal disease in EIAV-infected horses. To test this hypothesis, memory CTL (CTLm) responses were analyzed in two infected horses with high plasma viral loads and recurrent disease (progressors), and in two infected horses with low-to-undetectable viral loads and mild disease (nonpro ...[more]