Ontology highlight
ABSTRACT:
SUBMITTER: Imayama I
PROVIDER: S-EPMC3342840 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Imayama Ikuyo I Ulrich Cornelia M CM Alfano Catherine M CM Wang Chiachi C Xiao Liren L Wener Mark H MH Campbell Kristin L KL Duggan Catherine C Foster-Schubert Karen E KE Kong Angela A Mason Caitlin E CE Wang Ching-Yun CY Blackburn George L GL Bain Carolyn E CE Thompson Henry J HJ McTiernan Anne A
Cancer research 20120501 9
Obese and sedentary persons have increased risk for cancer; inflammation is a hypothesized mechanism. We examined the effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in 439 women. Overweight and obese postmenopausal women were randomized to 1-year: caloric restriction diet (goal of 10% weight loss, N = 118), aerobic exercise (225 min/wk of moderate-to-vigorous activity, N = 117), combined diet + exercise (N = 117), or control (N = 87). Baseline and 1-yea ...[more]