Ontology highlight
ABSTRACT:
SUBMITTER: Russell SL
PROVIDER: S-EPMC3343350 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
EMBO reports 20120501 5
Allergic asthma rates have increased steadily in developed countries, arguing for an environmental aetiology. To assess the influence of gut microbiota on experimental murine allergic asthma, we treated neonatal mice with clinical doses of two widely used antibiotics--streptomycin and vancomycin--and evaluated resulting shifts in resident flora and subsequent susceptibility to allergic asthma. Streptomycin treatment had little effect on the microbiota and on disease, whereas vancomycin reduced m ...[more]