Ontology highlight
ABSTRACT:
SUBMITTER: Hwang YJ
PROVIDER: S-EPMC3344252 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Hwang Yu-Jin YJ Kim Jaehyun J Park Dong-Sik DS Hwang Kyung-A KA
International journal of molecular sciences 20120418 4
Here we investigated the potential immune-enhancing activity of Isodon japonicus on murine splenocyte and natural-killer (NK) cells in vitro. The ethanol extract of I. japonicus significantly enhanced the proliferation of splenocyte and induced the significant enhancement of NK cells' activity against tumor cells (YAC-1). In addition, I. japonicus increased the production of interferon (IFN)-γ and tumor necrosis factor (TNF)-α, suggesting that the increase in NK cell cytotoxicity could be due to ...[more]