4-(4-Chloro-phen-yl)-2,6-bis-(1H-indol-3-yl)-1,4-dihydro-pyridine-3,5-dicarbo-nitrile ethanol monosolvate.

ABSTRACT: In the title compound, C(29)H(18)ClN(5)·C(2)H(6)O, the dihydro-pyridine ring adopts a strongly flattened envelope conformation, with a maximum deviation of 0.139?(2)?Å from its best plane for the Csp(3) atom. The dihedral angles between the dihydro-pyridine ring plane and the two indole rings in positions 2 and 6 are 34.28?(5) and 40.50?(6)°, respectively. In turn, the benzene ring and the dihydro-pyridine ring are oriented at a dihedral angle of 74.69?(6)°. An intra-molecular C-H?Cl hydrogen bond occurs. In the crystal, mol-ecules are linked by N-H?N, N-H?O and O-H?N hydrogen bonds into layers parallel to (001). There are short C-H?Cl contacts between mol-ecules in neighboring layers.

SUBMITTER: Zhu SL 

PROVIDER: S-EPMC3344446 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature