Ontology highlight
ABSTRACT:
SUBMITTER: Sabbagh MN
PROVIDER: S-EPMC3346261 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Current opinion in investigational drugs (London, England : 2000) 20100101 1
Latrepirdine (Dimebon) is a small-molecule compound under development by Medivation Inc and Pfizer Inc for the treatment of Alzheimer's disease and Huntington's chorea. Originally developed and marketed as an antihistamine in Russia, latrepirdine has since demonstrated potential for the treatment of neurodegenerative diseases. Early research suggested that the mechanism of action was centered on AChE inhibition and NMDA antagonism. More recent research questions these early findings, and other m ...[more]