Ontology highlight
ABSTRACT:
SUBMITTER: Pedersen JS
PROVIDER: S-EPMC3353015 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Pedersen Jan Skov JS Oliveira Cristiano L P CL Hübschmann Henriette Baun HB Arleth Lise L Manniche Søren S Kirkby Nicolai N Nielsen Hanne Mørck HM
Biophysical journal 20120515 10
Immune stimulating complex (ISCOM) particles consisting of a mixture of Quil-A, cholesterol, and phospholipids were structurally characterized by small-angle x-ray scattering (SAXS). The ISCOM particles are perforated vesicles of very well-defined structures. We developed and implemented a novel (to our knowledge) modeling method based on Monte Carlo simulation integrations to describe the SAXS data. This approach is similar to the traditional modeling of SAXS data, in which a structure is assum ...[more]