Ontology highlight
ABSTRACT:
SUBMITTER: Furger E
PROVIDER: S-EPMC3360681 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Furger Evelyne E Fedosov Sergey N SN Lildballe Dorte Launholt DL Waibel Robert R Schibli Roger R Nexo Ebba E Fischer Eliane E
PloS one 20120525 5
Haptocorrin (HC) is a circulating corrinoid binding protein with unclear function. In contrast to transcobalamin, the other transport protein in blood, HC is heavily glycosylated and binds a variety of cobalamin (Cbl) analogues. HC is present not only in blood but also in various secretions like milk, tears and saliva. No recombinant form of HC has been described so far. We report the expression of recombinant human HC (rhHC) in human embryonic kidney cells. We purified the protein with a yield ...[more]