Ontology highlight
ABSTRACT:
SUBMITTER: Sullner J
PROVIDER: S-EPMC3362350 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Süllner Julia J Lattrich Claus C Häring Julia J Görse Regina R Ortmann Olaf O Treeck Oliver O
Oncology letters 20110916 1
The nuclear receptor coactivator 7 (NCoA7) gene codes for an estrogen receptor-associated protein that plays a significant role in the cellular response to estrogens. Given that NCoA7 is expressed in the mammary gland, alterations in this gene may affect breast cancer risk. In this study, we compared the genotype and allele frequencies of the missense single nucleotide polymorphism (SNP) rs1567, located in the coding region of the NCoA7 gene and resulting in an amino acid exchange from asparagin ...[more]