Ontology highlight
ABSTRACT:
SUBMITTER: Shuang C
PROVIDER: S-EPMC5687632 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Oncotarget 20170814 51
Toll-like receptor 5 (TLR5) plays a fundamental role in immune responses. Recent findings suggest the TLR5 expression level affects cancer progression and development. In the present study, our examination of 256 breast carcinomas specimens revealed that TLR5 is overexpressed in breast carcinomas, and that TLR5 overexpression correlated with lymph node metastasis and cancer grade (p<0.01). In a case-control study, we also analyzed associations between TLR5 single nucleotide polymorphisms (SNPs) ...[more]