Ontology highlight
ABSTRACT:
SUBMITTER: Qi X
PROVIDER: S-EPMC3365781 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20120404 22
The Saccharomyces cerevisiae long terminal repeat retrotransposon Ty3 integrates within one or two nucleotides of the transcription initiation sites of genes transcribed by RNA polymerase III. In this study the minimal components required to re-constitute position-specific strand transfer by Ty3 integrase are defined. Ty3 integrase targeted by a synthetic fusion of RNA polymerase III transcription factor IIIB subunits, Brf1 and TBP, mediated position-specific strand transfer of duplex oligonucle ...[more]