Ontology highlight
ABSTRACT:
SUBMITTER: Thompson SD
PROVIDER: S-EPMC3366043 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Thompson Susan D SD Marion Miranda C MC Sudman Marc M Ryan Mary M Tsoras Monica M Howard Timothy D TD Barnes Michael G MG Ramos Paula S PS Thomson Wendy W Hinks Anne A Haas Johannes-Peter JP Prahalad Sampath S Bohnsack John F JF Wise Carol A CA Punaro Marilynn M Rosé Carlos D CD Pajewski Nicholas M NM Spigarelli Michael M Keddache Mehdi M Wagner Michael M Langefeld Carl D CD Glass David N DN
Arthritis and rheumatism 20120801 8
<h4>Objective</h4>In a genome-wide association study of Caucasian patients with juvenile idiopathic arthritis (JIA), we have previously described findings limited to autoimmunity loci shared by JIA and other diseases. The present study was undertaken to identify novel JIA-predisposing loci using genome-wide approaches.<h4>Methods</h4>The discovery cohort consisted of Caucasian JIA cases (n = 814) and local controls (n = 658) genotyped on the Affymetrix Genome-Wide SNP 6.0 Array, along with 2,400 ...[more]