Ontology highlight
ABSTRACT:
SUBMITTER: Pantelyushin S
PROVIDER: S-EPMC3366412 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Pantelyushin Stanislav S Haak Stefan S Ingold Barbara B Kulig Paulina P Heppner Frank L FL Navarini Alexander A AA Becher Burkhard B
The Journal of clinical investigation 20120501 6
Psoriasis is a common, relapsing inflammatory skin disease characterized by erythematous scaly plaques. Histological manifestations of psoriasis include keratinocyte dysregulation and hyperproliferation, elongated rete ridges, and inflammatory infiltrates consisting of T cells, macrophages, dendritic cells, and neutrophils. Despite the availability of new effective drugs to treat psoriasis, the underlying mechanisms of pathogenesis are still poorly understood. Recent studies have shown that Alda ...[more]