Ontology highlight
ABSTRACT:
SUBMITTER: Whale AS
PROVIDER: S-EPMC3367212 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Whale Alexandra S AS Huggett Jim F JF Cowen Simon S Speirs Valerie V Shaw Jacqui J Ellison Stephen S Foy Carole A CA Scott Daniel J DJ
Nucleic acids research 20120228 11
One of the benefits of Digital PCR (dPCR) is the potential for unparalleled precision enabling smaller fold change measurements. An example of an assessment that could benefit from such improved precision is the measurement of tumour-associated copy number variation (CNV) in the cell free DNA (cfDNA) fraction of patient blood plasma. To investigate the potential precision of dPCR and compare it with the established technique of quantitative PCR (qPCR), we used breast cancer cell lines to investi ...[more]