Ontology highlight
ABSTRACT:
SUBMITTER: Dispenzieri A
PROVIDER: S-EPMC3369677 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Dispenzieri Angela A Buadi Francis F Laumann Kristina K LaPlant Betsy B Hayman Suzanne R SR Kumar Shaji K SK Dingli David D Zeldenrust Steven R SR Mikhael Joseph R JR Hall Robert R Rajkumar S Vincent SV Reeder Craig C Fonseca Rafael R Bergsagel P Lief PL Stewart A Keith AK Roy Vivek V Witzig Thomas E TE Lust John A JA Russell Stephen J SJ Gertz Morie A MA Lacy Martha Q MQ
Blood 20120404 23
Immunoglobulin light-chain (AL) amyloidosis is a rare, incurable plasma cell disorder. Its therapy has benefited immensely from the expanding drug armamentarium available for multiple myeloma. Pomalidomide in combination with weekly dexamethasone (Pom/dex) is active among patients with relapsed myeloma. In the present study, we explored the Pom/dex combination in patients with previously treated AL. Patients were eligible for this prospective phase 2 trial if they had had at least one prior regi ...[more]