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Complete genome sequence of two novel Chinese virulent porcine reproductive and respiratory syndrome virus variants.

ABSTRACT: A highly pathogenic strain of porcine reproductive and respiratory syndrome virus (PRRSV), characterized by a discontinuous 30-amino-acid deletion in its Nsp2-coding region, has been emerging in China since 2006. Here, we report the complete genomic sequence of two novel Chinese virulent PRRSV variants with additional NSP2-gene deletions, which will help us understand the molecular and evolutionary characteristics of PRRSV in Asia.

SUBMITTER: Zhou Z

PROVIDER: S-EPMC3372213 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Complete genome sequence of two novel Chinese virulent porcine reproductive and respiratory syndrome virus variants.

Zhou Zhi Z Li Xiangdong X Liu Qi Q Hu Dongmei D Yue Xiaojuan X Ni Jianqiang J Yu Xiuling X Zhai Xinyan X Galliher-Beckley Amy A Chen Nanhua N Shi Jishu J Tian Kegong K

Journal of virology 20120601 11

A highly pathogenic strain of porcine reproductive and respiratory syndrome virus (PRRSV), characterized by a discontinuous 30-amino-acid deletion in its Nsp2-coding region, has been emerging in China since 2006. Here, we report the complete genomic sequence of two novel Chinese virulent PRRSV variants with additional NSP2-gene deletions, which will help us understand the molecular and evolutionary characteristics of PRRSV in Asia. ...[more]

PMID: 22570245

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