Ontology highlight
ABSTRACT:
SUBMITTER: Kabran P
PROVIDER: S-EPMC3372373 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Kabran Philomène P Rossignol Tristan T Gaillardin Claude C Nicaud Jean-Marc JM Neuvéglise Cécile C
DNA research : an international journal for rapid publication of reports on genes and genomes 20120224 3
Alternative pre-mRNA splicing is a major mechanism contributing to the proteome complexity of most eukaryotes, especially mammals. In less complex organisms, such as yeasts, the numbers of genes that contain introns are low and cases of alternative splicing (AS) with functional implications are rare. We report the first case of AS with functional consequences in the yeast Yarrowia lipolytica. The splicing pattern was found to govern the cellular localization of malate dehydrogenase, an enzyme of ...[more]