Ontology highlight
ABSTRACT:
SUBMITTER: Park KT
PROVIDER: S-EPMC3376909 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Park Kyung-Tae KT Wu Wei W Lovell Scott S Lutkenhaus Joe J
Molecular microbiology 20120607 2
MinD is a component of the Min system involved in the spatial regulation of cell division. It is an ATPase in the MinD/ParA/Mrp deviant Walker A motif family which is within the P loop GTPase superfamily. Its ATPase activity is stimulated by MinE; however, the mechanism of this activation is unclear. MinD forms a symmetric dimer with two binding sites for MinE; however, a recent model suggested that MinE occupying one site was sufficient for ATP hydrolysis. By generating heterodimers with one bi ...[more]