Ontology highlight
ABSTRACT:
SUBMITTER: Akam T
PROVIDER: S-EPMC3378654 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Akam Thomas T Oren Iris I Mantoan Laura L Ferenczi Emily E Kullmann Dimitri M DM
Nature neuroscience 20120501 5
Gamma oscillations in the dentate gyrus and hippocampal CA3 show variable coherence in vivo, but the mechanisms and relevance for information flow are unknown. We found that carbachol-induced oscillations in rat CA3 have biphasic phase-response curves, consistent with the ability to couple with oscillations in afferent projections. Differences in response to stimulation of either the intrinsic feedback circuit or the dentate gyrus were well described by varying an impulse vector in a two-dimensi ...[more]