Ontology highlight
ABSTRACT:
SUBMITTER: Stancakova A
PROVIDER: S-EPMC3379649 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Stancáková Alena A Civelek Mete M Saleem Niyas K NK Soininen Pasi P Kangas Antti J AJ Cederberg Henna H Paananen Jussi J Pihlajamäki Jussi J Bonnycastle Lori L LL Morken Mario A MA Boehnke Michael M Pajukanta Päivi P Lusis Aldons J AJ Collins Francis S FS Kuusisto Johanna J Ala-Korpela Mika M Laakso Markku M
Diabetes 20120502 7
We investigated the association of glycemia and 43 genetic risk variants for hyperglycemia/type 2 diabetes with amino acid levels in the population-based Metabolic Syndrome in Men (METSIM) Study, including 9,369 nondiabetic or newly diagnosed type 2 diabetic Finnish men. Plasma levels of eight amino acids were measured with proton nuclear magnetic resonance spectroscopy. Increasing fasting and 2-h plasma glucose levels were associated with increasing levels of several amino acids and decreasing ...[more]