Ontology highlight
ABSTRACT:
SUBMITTER: Ross JA
PROVIDER: S-EPMC3381932 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Ross Julie A JA Linabery Amy M AM Blommer Crystal N CN Langer Erica K EK Spector Logan G LG Hilden Joanne M JM Heerema Nyla A NA Radloff Gretchen A GA Tower Richard L RL Davies Stella M SM
Pediatric blood & cancer 20120315 1
<h4>Background</h4>The mixed lineage leukemia (MLL) gene is commonly rearranged in infant leukemia (IL). Genetic determinants of susceptibility to IL are unknown. Recent genome-wide association studies for childhood acute lymphoblastic leukemia (ALL) have identified susceptibility loci at IKZF1, ARID5B, and CEBPE.<h4>Procedure</h4>We genotyped these loci in 171 infants with leukemia and 384 controls and evaluated associations overall, by subtype [ALL, acute myeloid leukemia (AML)], and by presen ...[more]