Ontology highlight
ABSTRACT:
SUBMITTER: Tong CC
PROVIDER: S-EPMC3384658 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Tong Charles C L CC Ko Eric C EC Sung Max W MW Cesaretti Jamie A JA Stock Richard G RG Packer Stuart H SH Forsythe Kevin K Genden Eric M EM Schwartz Myron M Lau K H Vincent KH Galsky Matthew M Ozao-Choy Junko J Chen Shu-Hsia SH Kao Johnny J
PloS one 20120627 6
<h4>Background</h4>Preclinical data suggest that sunitinib enhances the efficacy of radiotherapy. We tested the combination of sunitinib and hypofractionated image-guided radiotherapy (IGRT) in a cohort of patients with historically incurable distant metastases.<h4>Methods</h4>Twenty five patients with oligometastases, defined as 1-5 sites of active disease on whole body imaging, were enrolled in a phase II trial from 2/08 to 9/10. The most common tumor types treated were head and neck, liver, l ...[more]