Ontology highlight
ABSTRACT:
SUBMITTER: Gregory LG
PROVIDER: S-EPMC3385347 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Gregory L G LG Causton B B Murdoch J R JR Mathie S A SA O'Donnell V V Thomas C P CP Priest F M FM Quint D J DJ Lloyd C M CM
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090622 10
<h4>Background</h4>Inhaled house dust mite (HDM) results in T-helper (TH) 2 type pathology in unsensitized mice, in conjunction with airway hyperreactivity and airway remodelling. However, the pulmonary cytokine and chemokine profile has not been reported.<h4>Methods</h4>We have performed a time course analysis of the characteristic molecular mediators and cellular influx in the bronchoalveolar lavage (BAL) and lung in order to define the pulmonary inflammatory response to inhaled HDM extract. M ...[more]