Ontology highlight
ABSTRACT:
SUBMITTER: Ng KW
PROVIDER: S-EPMC3387273 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Ng Kenneth W KW O'Conor Christopher J CJ Kugler Lindsay E LE Cook James L JL Ateshian Gerard A GA Hung Clark T CT
Annals of biomedical engineering 20110721 10
The purpose of the presented work is to examine the response of engineered cartilage to a transient, 2-week application of anabolic growth factors compared to continuous exposure in in vitro culture. Immature bovine chondrocytes were suspended in agarose hydrogel and cultured for 28 days (Study 1) or 42 days (Study 2) in chondrogenic media with TGF-β1, TGF-β3, or IGF-I either added for only the first 14 days in culture or added to the media for the entire study period. In both studies, there wer ...[more]